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NCJ Number: 228590 Find in a Library
Title: Structural Neuroimaging and the Antisocial Brain: Main Findings and Methodological Challenges
Journal: Criminal Justice and Behavior  Volume:36  Issue:11  Dated:November 2009  Pages:1163-1176
Author(s): Stephane A. De Brito; Sheilagh Hodgins; Eamon J.P. McCrory; Andrea Mechelli; Marko Wilke; Alice P. Jones; Essi Viding
Date Published: November 2009
Page Count: 14
Sponsoring Agency: Economic and Social Research Council (ESRC)
Swindon SN2 1UJ,
National Institute for Health Research
London, SW1A 2NL
South London and Maudsley NHS Foundation Trust
London, SE5 8AZ
UK Medical Research Council
London , W1B 1AL
Grant Number: G0401170;RES-061-25-0189
Type: Report (Study/Research)
Format: Article
Language: English
Country: United States of America
Annotation: This article examines the use of analysis of covariance (ANCOVA) in brain-imaging studies.
Abstract: Four checks on previously published results (De Brito et al. 2009) were conducted. First, whether the original ANCOVA violated the assumption of homogeneity of regression slopes between the covariates and the dependent variable in the study groups was investigated. Results show that the assumption had not been violated. Examined second was whether the original ANCOVA violated the assumption of a linear association between the covariates and the dependent variable. This assumption was not violated. Third, regions of interests (ROIs) were assessed to find whether the original findings would remain if the variance associated with the covariates was included in the analyses. Finally, it was assessed whether the study had failed to identify gray matter concentration (GMC) differences in the whole-brain analysis by throwing away variance associated with Full Scale Intelligence Quotient (FSIQ) and hyperactivity-inattention symptoms. Results showed that the boys with conduct problems and callous-unemotional traits (CP/CU+) differed from the typically developing (TD) boys in two additional brain regions: the middle occipital gyrus and the right precuneus. Data were collected from 23 boys, 10 to 13-years old, without diagnosed neurological, medical, or psychiatric problems. Table, figures, and references
Main Term(s): Genetic influences on behavior; Juvenile delinquency research
Index Term(s): Behavior modification; Behavioral science research; Juvenile Delinquent behavior; Juvenile Delinquent-nondelinquent comparisons; Misconduct
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