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NCJ Number: 229590 Find in a Library
Title: Comparative Analysis of Two Different Sets of Y-Chromosome Short Tandem Repeats (Y-STRs) on a Common Population Panel
Journal: Forensic Science International: Genetics  Volume:4  Issue:1  Dated:December 2009  Pages:11-20
Author(s): Julie L. Maybruck; Erin Hanson; Jack Ballantyne; Bruce Budowle; Paul A. Fuerst
Date Published: December 2009
Page Count: 10
Type: Report (Technical)
Format: Article
Language: English
Country: Ireland
Annotation: A comparative analysis of two Y-STR loci sets was conducted on a population sample of 224 individuals, 114 Caucasians and 110 African-Americans.
Abstract: One set of loci, designated the OSU 10-locus set, comprises variable, single copy, male-specific loci that are dispersed across the Y-chromosome. Parallel evaluations were performed using the 10 Y-chromosome loci most frequently used for forensic analysis, the loci chosen as the SWGDAM Y-STR loci. The OSU 10-locus set had a greater average number of alleles per locus and higher average gene diversity than the SWGDAM loci. The OSU 10-locus set found 220 unique haplotypes in 224 individuals. In approximately 6000 pairwise haplotype comparisons for each population with each set of loci, the OSU 10-locus set also yielded a greater average number of allelic differences per pair than the SWGDAM loci. Finally, the overall linkage disequilibrium levels were lower for the OSU 10-locus set in the Caucasian population. In general, the OSU 10-locus set revealed a higher power of discrimination than the SWGDAM set. Tables, figures, appendix, and references (Published Abstract)
Main Term(s): Forensic sciences
Index Term(s): Comparative analysis; Criminalistics; Evaluation measures; Forensic medicine; Scientific techniques
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