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NCJ Number: 236676 Find in a Library
Title: Genetic Analysis of the Presumptive Blood From Louis XVI, King of France
Journal: Forensic Science International: Genetics  Volume:5  Issue:5  Dated:November 2011  Pages:459-463
Author(s): Carles Lalueza-Fox; Elena Gigli; Carla Bini; Francesc Calafell; Donata Luiselli; Susi Pelotti; Davide Pettener
Date Published: November 2011
Page Count: 5
Sponsoring Agency: Ministerio de Ciencia e Innovacion
28027 Madrid,
Publisher: http://www.elsevier.com 
Type: Report (Study/Research)
Format: Article
Language: English
Country: Ireland
Annotation: This study focused on the ancient DNA analysis of Louis XVI, king of France.
Abstract: A text on a pyrographically decorated gourd dated to 1793 explains that it contains a handkerchief dipped with the blood of Louis XVI, king of France, after his execution. Biochemical analyses confirmed that the material contained within the gourd was blood. The mitochondrial DNA (mtDNA) hypervariable region 1 (HVR1) and 2 (HVR2), the Y-chromosome STR profile, some autosomal STR markers and a SNP in HERC2 gene associated to blue eyes, were retrieved, and some results independently replicated in two different laboratories. The uncommon mtDNA sequence retrieved can be attributed to a N1b haplotype, while the novel Y-chromosome haplotype belongs to haplogroup G2a. The HERC2 gene showed that the subject analyzed was a heterozygote, which is compatible with a blue-eyed person, as king Louis XVI was. To confirm the identity of the subject, an analysis of the dried heart of his son, Louis XVII, could be undertaken. (Published Abstract)
Main Term(s): Forensic sciences
Index Term(s): Blood/body fluid analysis; DNA fingerprinting; Foreign criminal justice research; Investigative techniques; Parentage determination; Spain
To cite this abstract, use the following link:
http://www.ncjrs.gov/App/publications/abstract.aspx?ID=258691

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