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NCJ Number: 30340 Add to Shopping cart Find in a Library
Title: EQUIPMENT SYSTEMS IMPROVEMENT PROGRAM - PERSISTENCE OF SELECTED GENETIC MARKERS IN DRIED BLOOD
Author(s): G C DENAULT; H H TAKIMOTO; Q Y KWAN
Corporate Author: Aerospace Corporation
United States of America
Date Published: 1975
Page Count: 85
Sponsoring Agency: Aerospace Corporation
El Segundo, CA 90245
National Institute of Justice/
Rockville, MD 20849
US Dept of Justice

US Dept of Justice NIJ Pub
Washington, DC 20531
Contract Number: J-LEAA-025-73
Publication Number: ATR-75(7910)-1
Sale Source: National Institute of Justice/
NCJRS paper reproduction
Box 6000, Dept F
Rockville, MD 20849
United States of America
Document: PDF
Language: English
Country: United States of America
Annotation: THE PERSISTENCE OF SELECTED GENETICALLY DERIVED CONSTITUTENTS IN DRIED HUMAN BLOOD WAS INVESTIGATED OVER A SIX-MONTH PERIOD.
Abstract: BLOOD WAS DEPOSITED ON SIX SUBSTRATES: GLASS, WOOL, NYLON, AND THREE TYPES OF PURE COTTON (PLAIN COTTON, PERMA PRESS, AND DENIM), AND THE RESULTING DRIED BLOOD SPECIMENS WERE AGED AT AMBIENT TEMPERATURE UNDER 20 AND 66 PERCENT RELATIVE HUMIDITY CONDITIONS. ANALYSES WERE PERFORMED AT 1, 2, 4, 13, AND 26 WEEK AGING PERIODS. RED CELL ANTIGEN SYSTEMS EVALUATED IN THIS STUDY INCLUDED ABO, MN, RH, KIDD, DUFFY, AND KELL. THE MOST STABLE ANTIGENS AMONG THOSE INVESTIGATED WERE A,B,AND O OF ABO; M, N, AND S OF MN; AND D OF THE RH SYSTEM. THESE VARIANTS WERE IDENTIFIED IN SPECIMENS THAT WERE AGED FOR 26 WEEKS AT THE LOW AND HIGH RELATIVE HUMIDITY CONDITIONS. THE LEAST STABLE VARIANTS ARE ALSO IDENTIFIED. FOUR ENZYME SYSTEMS ALSO INCLUDED IN THIS STUDY WERE AK, ADA, PGM, AND EAP. THE PROBABILITY FOR TWO RANDOMLY SELECTED INDIVIDUALS TO HAVE THE SAME COMBINATION OF VARIANTS WAS CALCULATED FOR EACH TEST PERIOD, BASED ONLY ON THE PERSISTING GENETIC MARKERS INCLUDED IN THE STUDY, USING BLOOD FREQUENCY OF OCCURRENCE DATA IN THE LITERATURE, AND ASSUMING NO ASSAY ERRORS. DISCRIMINATION OF ONE IN 2500 IS POSSIBLE AT ONE WEEK FOR EITHER HUMIDITY STORAGE CONDITION. AT 26 WEEKS, HOWEVER, THE VALUES ARE ONE IN 65 AND ONE IN 28 FOR AGING AT AMBIENT TEMPERATURE UNDER 20 AND 66 PERCENT RELATIVE HUMIDITY LEVELS, RESPECTIVELY. ADDITIONAL FACTORS AFFECTING THE DISCRIMINATION PROBABILITY ARE INCLUDED. (AUTHOR ABSTRACT)
Index Term(s): Blood/body fluid analysis; Evidence identification; Forensic medicine; Suspect identification; Testing and measurement
To cite this abstract, use the following link:
http://www.ncjrs.gov/App/publications/abstract.aspx?ID=30340

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