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NCJRS Abstract

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NCJ Number: 44095 Find in a Library
Title: TREATMENT FOR SURVIVAL PRIOR TO DEATH AND INTERPRETATION OF POSTMORTEM TOXICOLOGIC FINDINGS (FROM GUIDE TO THE INVESTIGATION AND REPORTING OF DRUG-ABUSE DEATHS PROBLEMS AND METHODS, BY L A GOTTSCHALK - SEE NCJ-44092)
Author(s): E G COMSTOCK
Date Published: 1977
Page Count: 4
Sponsoring Agency: National Institute of Justice/
Rockville, MD 20849
US Dept of Health, Education, and Welfare
Rockville, MD 20857
Grant Number: 3H81 DA 01466-0 ISI
Sale Source: National Institute of Justice/
NCJRS paper reproduction
Box 6000, Dept F
Rockville, MD 20849
United States of America
Document: PDF|PDF
Language: English
Country: United States of America
Annotation: CIRCUMSTANCES WHICH INFLUENCE THE INTERPRETATION OF TOXICOLOGIC FINDINGS AT POSTMORTEM EXAMINATIONS, SUCH AS THE ADMINISTRATION OF DRUGS DURING TREATMENT PRIOR TO DEATH, ARE DISCUSSED.
Abstract: IT IS STRESSED THAT ANALYTICAL DATA RESULTING FROM TOXICOLOGIC EXAMINATION ARE GENERALLY INSUFFICIENT TO ATTRIBUTE CAUSE OF DEATH TO ANY ONE SUBSTANCE. RESULTS MUST BE INTERPRETED WITH CONSIDERATION GIVEN TO INVESTIGATIONS AT THE SCENE, ACTIVITIES OF THE DECEDENT IMMEDIATELY PRIOR TO DEATH, FIRST AID OR TREATMENT EFFORTS PROVIDED BY LAYPERSONS OR BY MEDICAL PERSONNEL, AND LONG-TERM DRUG USE HISTORY. INDIVIDUALS MAY BE MADE MORE SUSCEPTIBLE TO SOME SUBSTANCES BY PREEXISTING PATHOLOGY OR LESS SUSCEPTIBLE BY TOLERANCE. DIFFERENCES IN SUSCEPTIBILITY TO TOXIC SUBSTANCES ARE DETERMINED IN PART BY GENETIC FACTORS. A DISCUSSION OF THE PHARMACODYNAMICS OF HOST-SUBSTANCE RELATIONSHIPS INCLUDES CONSIDERATION OF CARBON MONOXIDE AND BARBITUATES. A METHOD OF DETERMINING TOLERANCE TO SEDATIVE DRUGS IS DESCRIBED AND GRAPHICALLY ILLUSTRATED. FACTORS TO CONSIDER IN INTERPRETING TOXICOLOGIC FINDINGS ARE LISTED.
Index Term(s): Autopsy; Drug testing; Forensic medicine; Poisons and poison analysis; Toxic reactions
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http://www.ncjrs.gov/App/publications/abstract.aspx?ID=44095

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