skip navigation

PUBLICATIONS

Register for Latest Research

Stay Informed
Register with NCJRS to receive NCJRS's biweekly e-newsletter JUSTINFO and additional periodic emails from NCJRS and the NCJRS federal sponsors that highlight the latest research published or sponsored by the Office of Justice Programs.

NCJRS Abstract

The document referenced below is part of the NCJRS Virtual Library collection. To conduct further searches of the collection, visit the Virtual Library. See the Obtain Documents page for direction on how to access resources online, via mail, through interlibrary loans, or in a local library.

 

NCJ Number: 64015 Find in a Library
Title: SIGNIFICANCE OF DRUG ANALYSIS OF SWEAT IN RESPECT TO RAPID SCREENING FOR DRUG ABUSE
Journal: ZEITSCHRIFT FUER RECHTSMEDIZIN  Volume:82  Issue:4  Dated:(1979)  Pages:251-256
Author(s): I ISHIYAMA; T NAGAI; T NAGAI; E KOMURO; T MOMOSE; N AKIMORI
Corporate Author: Springer-Verlag
United States of America
Date Published: 1979
Page Count: 6
Sponsoring Agency: Springer-Verlag
Secaucus, NJ 07094
Type: Report (Study/Research)
Format: Article
Language: English
Country: West Germany (Former)
Annotation: MORPHINE AND METHAMPHETAMINE ARE SHOWN TO BE EXCRETED IN SWEAT, SO AS TO PERMIT DETECTION BY THE SEROLOGICAL AND PHYSICOCHEMICAL TECHNIQUES USED IN URINARY EXAMINATIONS.
Abstract: AFTER GIVING 10 MG OF MORPHINE HYDROCHLORIDE OR METHAMPHETAMINE HYDROCHLORIDE ORALLY TO VOLUNTEERS, URINE AND SWEAT WERE COLLECTED IN INTERVALS. THE SWEAT WAS COLLECTED BY RUBBING THE SKIN WITH COTTON OR A TOWEL AT 50 DEGREES CENTIGRADE. FOR THE DETECTION OF MORPHINE, THE SWEAT EXTRACT WAS FREEZE-DRIED WITH THE AID OF ROTARY EVAPORATION. HOMOGENEOUS ENZYME IMMUNOASSAY WAS USED FOR THE TESTS OF THE URINE AND SWEAT. THE SWEAT EXAMINATION PRODUCED THE SAME ACCURACY AND CUT-OFF LEVEL AS THE URINE TEST. THE PRESENCE OF MORPHINE IN THE SWEAT COULD ALSO BE CONFIRMED BY GASCHROMATOGRAPHIC AND GASCHROMATOGRAPHY-MASS SPECTROMETRIC ANALYSIS ACCORDING TO THE METHOD OF WILKINSON ET AL. THE CONDENSION OF THE SWEAT EXTRACT BY FREEZE-DRYING OR EVAPORATION COULD NOT BE ACHIEVED FOR THE METHAMPHETAMINE BECAUSE OF ITS HIGH VOLATILITY. THE DRUG WAS EXTRACTED ACCORDING TO THE METHOD OF JAIN. THE EXCRETION OF THE DRUG INTO THE SWEAT REACHED ABOUT THE SAME AMOUNT AS WAS ELIMINATED THROUGH THE URINE. GASCHROMATOGRAPHY WAS USED TO DETECT THE METHAMPHETAMINE. THE TESTING OF SWEAT TO DETERMINE DRUG USE IS PRACTICAL WHERE THE SUBJECT REFUSES TO DELIVER OTHER SPECIMENS. MANY ALKALOIDS AND BARBITURATES ARE EXCRETED IN THE SWEAT ALSO, AND CAN BE DETECTED QUANTITATIVELY BY THE SAME PRINCIPLES USED IN THE EXPERIMENT. GRAPHIC AND TABULAR DATA AND REFERENCES ARE PROVIDED. (RCB)
Index Term(s): Criminalistics; Drug detection; Drug research; Drug testing; Forensic medicine
To cite this abstract, use the following link:
http://www.ncjrs.gov/App/publications/abstract.aspx?ID=64015

*A link to the full-text document is provided whenever possible. For documents not available online, a link to the publisher's website is provided. Tell us how you use the NCJRS Library and Abstracts Database - send us your feedback.