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NCJRS Abstract

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  NCJ Number: NCJ 179419   Add to Shopping cart   Find in a Library
  Title: Improved Analysis of DNA Short Tandem Repeats with Time-of-Flight Mass Spectrometry Final Report
  Document URL: PDF 
  Author(s): John M. Butler ; Christopher H. Becker
  Date Published: 1999
  Page Count: 164
  Annotation: This report describes new technology for rapid and accurate analysis of DNA short tandem repeat (STR) markers using time-of-flight mass spectrometry.
  Abstract: The report includes: (1) Executive Summary (descriptions of Gene Trace Systems and Mass Spectrometry, Short Tandem Repeats and Single Nucleotide Polymorphisms and Papers Published and Presentations Made); (2) Project Description and Grants; (3) Scope and Methodology (Assay Development and Primer Testing, Sample Cleanup and Mass Spectrometry, Sample Genotyping, Comparison Tests With ABI 310); (4) Results and Discussion for STR Analysis by Mass Spectrometry (Marker Selection and Feasibility Studies, Multiplex STR Work, Comparison Tests Between ABI 310 and Mass Spec Results, PCR Issues, Analytical Capabilities of Mass Spec); (5) Results and Discussion for Multiplex SNPs (Mitochondrial DNA Work, Y Chromosome Work); and (6) Conclusions and Implications of Findings. Notes, references, figures, tables
  Main Term(s): Criminology
  Index Term(s): Crime Laboratories (Crime Labs) ; Crime laboratory equipment ; Evidence identification and analysis ; Research methods ; Science and Technology ; Mass spectroscopy ; Forensics/Forensic Sciences ; Scientific techniques ; DNA fingerprinting
  Sponsoring Agency: National Institute of Justice (NIJ)
US Department of Justice
Office of Justice Programs
United States of America
  Grant Number: 97-LB-VX-0003
  Sale Source: National Institute of Justice/NCJRS
Box 6000
Rockville, MD 20849
United States of America

NCJRS Photocopy Services
Box 6000
Rockville, MD 20849-6000
United States of America
  Type: Report (Technical)
  Country: United States of America
  Language: English
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