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NCJ Number: NCJ 219503   Add to Shopping cart   Find in a Library
Title: Generating More Precise Post Mortem Interval Estimates With Entomological Evidence: Reliable Patterns of Gene Expression Throughout Calliphorid Larval and Pupal Development, Final Report
Author(s): Dr. David Foran
Corporate Author: Michigan State University
United States of America
Date Published: 2007
Page Count: 189
Sponsoring Agency: National Institute of Justice
US Department of Justice
Office of Justice Programs
United States of America
Grant Number: 2004-DN-BX-K005
Sale Source: National Institute of Justice/NCJRS
Box 6000
Rockville, MD 20849
United States of America

NCJRS Photocopy Services
Box 6000
Rockville, MD 20849-6000
United States of America
Document: PDF 
Type: Report (Technical)
Language: English
Country: United States of America
Annotation: In this federally supported research, gene expression information was incorporated into the age estimation process (of the blow fly) in order to better define a postmortem interval (PMI).
Abstract: The research undertaken in this study has advanced the ability of an investigator to estimate postmortem interval (PMI) derived from blow fly evidence by providing new tools, tools that significantly increase the accuracy and precision of age predictions. The basic theory upon which the entire project was based, that gene expression can provide more precise age estimates, was established, and was most successful in developmental stages that are currently the most difficult to assess. At the same time, laboratory rearing conditions for blow flies that most accurately mimic those on a cadaver were generated, creating a standardized operating procedure that helps meet the tenets of Daubert. Likewise, the modeling of larval growth (length and weight), along with gene expression, allows for confidence intervals and error estimates to be produced. In total, the works performed have produced a substantial leap forward in using entomological data to more accurately estimate time since death. Blow fly evidence can be useful in estimating PMI during death investigations. This is due largely to the reliable development of blow flies and their fondness for colonizing remains within hours of death. Investigators can utilize blow fly evidence as a biological clock, using the evidentiary flies to backtrack to the time that remains were colonized. This research study, supported by the U.S. Department of Justice, National Institute of Justice (NIJ), utilized gene expression information in age estimates of the green bottle fly. This species was chosen because it is forensically useful and globally distributed. Tables, figures, and appendixes
Main Term(s): Time of death determination
Index Term(s): Coroners ; Evidence identification and analysis ; Forensic medicine ; Autopsy ; Criminalistics ; Forensics/Forensic Sciences ; NIJ final report ; NIJ grant-related documents
   
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https://www.ncjrs.gov/App/Publications/abstract.aspx?ID=241295

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