Relevant legislation, definitions, and evidentiary issues are examined with respect to antitrust violations, bribery, computer crime, conflict of interest, embezzlement, false claims and statements, and food and drug violations. Other crimes considered include contract fraud, foreign corrupt practices, criminal copyright fraud, perjury, mail and wire fraud, theft of trade secrets, tax and security fraud, witness tampering, and violations of the travel Act. The Racketeer Influenced and Corrupt Organizations (RICO) Act is reviewed and its effect on organized crime involvement in business is discussed. Procedural issues relating to white-collar crimes and their prosecution then are evaluated. These include issues relating to administrative summons, attorney-client privilege, discovery, fifth amendment limitations on compelled production of evidence, grand jury subpoenas, immunity, parallel civil and criminal suits, and sentencing. Article footnotes.