The students were all in their fourth and final year of secondary school in the Abeokuta local government area of the State of Ogun. The 534 males and 377 females had an average age of 16.4. Eighty-nine percent were from the lower or middle socioeconomic levels. They completed self-report questionnaires in September 1986. Findings showed that the most commonly used drugs were salicylate analgesics, mild stimulants, alcohol, antibiotics, and diazepam. Low use was reported for barbituates, cannabis, organic solvents, and cocaine. No students reported use of narcotic analgesics or hallucinogens. Females used diazepam significantly more than males. Most users had their first contact with drugs in primary school. Results indicate the need for a viable prevention program and a comprehensive database in Ogun. Tables and 19 references. (Author abstract modified)