Medical aspects of AIDS are outlined, including transmission, high-risk groups, progression of the disease, and antibody testing. Although the behaviors through which AIDS is transmitted do not occur during the regular conduct of probation supervision, administrators must develop policies that combine scientific knowledge, agency priorities, and social conscience. The safety of probation officers as well as the rights of AIDS patients must be protected. Probation is obliged to work toward the discontinuation of intravenous drug use and educate supervised persons about AIDS and high-risk behaviors. Recommended strategy elements for probation to respond to AIDS include training, verification and medical treatment, confidentiality, urine monitoring, education, supervision, and testing. A resource list is provided. 10 appendixes.