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Highly Polymorphic Minisatellite DNA Probes: Further Evaluation for Individual Identification and Paternity Testing

NCJ Number
123912
Journal
Journal of the Forensic Science Society Volume: 30 Issue: 1 Dated: (January/February 1990) Pages: 3-18
Author(s)
J C Smith; C R Newton; A Alves; R Anwar; D Jenner; A F Markham
Date Published
1990
Length
16 pages
Annotation
Research on deoxyribonucleic acid (DNA) fingerprint patterns in 50 persons confirmed earlier studies showing the potential usefulness of this approach in paternity testing and forensic analysis for the identification of suspects and victims.
Abstract
Reliable and useful laboratory protocols have been developed for the routine DNA fingerprinting of individuals using the highly polymorphic minisatellite DNA probes 33.15 and 33.6. Comparisons of DNA fingerprinting from the 50 additional individuals provided further data on the level of band sharing in the DNA fingerprints of unrelated individuals as well as on the number of bands that can be scored in individuals. The results were consistent with earlier studies and provided further support for the Mendelian inheritance of minisatellite loci and for the lack of significant allelism and linkage between different variable DNA fragments detected in a human DNA fingerprint. Results indicate the usefulness of multilocus probes 33.15 and 33.6 in Caucasian populations. Studies of other ethnic groups have also been completed. Figures, tables, and 32 references. (Author abstract modified)