The paper examines various drugs -- alcohol, sedative hypnotics, stimulants, hallucinogens, opioids, phencyclidine, cannabis, and inhalants -- and the states of intoxication induced by them, as well as ways in which anger and violence are modulated in such states. These drugs can affect brain function in different ways, through intoxication, withdrawal, organic mental disorders, and psychotic states. The chapter explores drug effects on each type of clinical syndrome, and examines how anger and violence are relevant dimensions of these syndromes. 2 tables and 78 references