Part 1 contains two papers and comments on the demand for tobacco products. One paper presents an econometric analysis of the effects of prices and tobacco control policies on the probability of cigarette smoking and other tobacco use among adults. The second paper confirms the inverse relationship between price and cigarette smoking. Part 2 contains two papers on alcohol use and abuse. One paper presents the findings from an experimental analysis of alcohol consumption in rats; and the second paper considers the rationality of alcohol consumption in a review of experimental studies on the relationship between temporal discounting and drinking. The two papers in Part 3 consist of reports on econometric and behavioral analyses of the demand for illicit drugs, focusing on the demands for cocaine and marijuana. One study found that youth drug use is more sensitive to price than adult drug use. Another study addressed the implications of behavioral economic research for strategies aimed at reducing cocaine use. The two papers of Part 4 consider the relationships between the demands for the various substances discussed in the first three parts of the volume. In the last two parts of the volume, the emphasis shifts to the relationships between employment and income and substance use and abuse. Chapter tables and references and author and subject indexes