When catastrophic crime occurs, it is essential to have established protocols, plans, and training in place to respond effectively. To address the extraordinary chain of mass violence, the National Association of Crime Victim Compensation Boards examined the role of compensation programs during a mass casualty incident and outlined a strategy for effectively serving victims, survivors, allied victim professionals, and compensation program staff. This report presents the Mass-Casualty Protocol for Victim Compensation Programs. The design of the protocol provides a standard operating procedure for compensation programs to follow during a mass-casualty incident. The protocol is divided into three stages with specific steps involved. These stages include: before a crisis, during a crisis, and after a crisis. Additional information is provided in the appendixes to include: program guidelines/statutes, networking, resources, statistics, mass violence/terrorism, media management, victim assistance resources, Office for Victims of Crime (OVC) protocol, and sample applications.