The study found that an AgNO3/La(NO3)3 reagent provides an enhanced detection of GHB by improving the visualization of GHB characteristic crystals and a lower detection limit in aqueous solution of 0.5 mg/ml. GHB was positively distinguished among a range of GHB precursors, structure-related compounds, and other control substances using the enhanced test. The enhanced regent does allow GHB detection in only a limited range of beverages. Citric acid was identified as an interferant that will produce false negative results when its concentration is greater than GHB. Because of its central nervous system depressant properties, GHB induces a range of effects from relaxation and euphoria, confusion, dizziness, nausea, and short-term amnesia, to uncontrollable shaking and seizures, respiratory depression, and unarousable unconsciousness. GHB has become one of the most frequently encountered drugs of abuse and malevolent purpose in the club drug scene. Descriptions of materials and methods address the preparation of reagents and dry samples, as well as procedures of the experiments. 3 figures, 2 tables, and 16 references