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Unusual Case of Identification by DNA Analysis of Siblings

NCJ Number
237528
Journal
Forensic Science International: Genetics Volume: 6 Issue: 1 Dated: January 2012 Pages: 121-123
Author(s)
Franz Neuhuber; Max P. Baur; Jan Cemper-Kiesslich; Bettina Dunkelmann; Fabio Monticelli
Date Published
January 2012
Length
3 pages
Annotation
This paper discusses DNA identification using samples from siblings.
Abstract
A badly decomposed body required identification by means of DNA analysis. A brother and sister of the deceased were available as reference subjects. Although investigation of Y-chromosomal markers established an exclusion condition, autosomal markers suggested a positive identification. In order to increase the reliability of the tests, X-chromosomal markers were also investigated. This analysis showed the body to have an XXY genotype (Klinefelter's syndrome). A number of hypotheses were assessed using biostatistical methods, ultimately resulting in a definite identification. The special aspect of Klinefelter's syndrome proved highly useful for biostatistical analysis. (Published Abstract)