The document is intended as a practical reference to allow interested persons, agencies, and communities to make an informed decision about a program's appropriateness for their local situation, needs, and available resources. An introduction notes that demand for effective violence and crime prevention programs has never been greater, but most programs being used have not been evaluated. Therefore, a collaborative effort was conducted to identify 10 violence prevention programs that met a high scientific standard of program effectiveness, based on their strong research design, data indicating significant deterrent effects, sustained effects, and multiple site replication. The project included plans for a technical assistance and monitoring component. Prenatal and Infancy Home Visitation by Nurses consists of intensive and comprehensive home visitation by nurses during a woman's pregnancy and the first 2 years after birth of the woman's first child. The program is designed to serve low-income, at-risk pregnant women bearing their first child. The program aims to help women improve their prenatal health and the outcomes of pregnancy, improve the care of infants and toddlers, and improve the women's own personal development. The program has been tested in rural and urban settings with white and black families. The program reduced child abuse and neglect, maternal behavior problems due to alcohol and drug abuse, maternal arrests, and children's alcohol abuse and arrests at age 15. The program costs were recovered by the child's fourth birthday. Figures, tables, appended program materials, reference notes, and 148 references