Information collection methods and sources included ethnographic information, print media, Internet-based information, law enforcement, victim advocacy, policymakers, and pharmaceutical industry interests. The analysis took into account a considerable amount of conflicting information and differing viewpoints. Five trials involving eight defendants and the use of the drug flunitrazepam (Rohypnol) have taken place in State courts since 1993. In addition, two trials have occurred in which defendants were charged with drug-facilitated rape using gamma-hydroxybutyrate (GHB). Other cases have involved victim beliefs that they were drugged or raped or have not involved action beyond initial investigation of the incident. Findings also indicated that potential exists for increasing numbers of incidents of drug-facilitated rape. The circumstances that set the stage for the series of drug-facilitated rapes verified to date are new in some instances and may become enduring features of the culture. Findings suggested the need for further research, as well as action in the areas of sexual assault prevention and education, investigation and prosecution practices, and training for professionals. Figures, tables, list of media search terms, and 48 references (Author abstract modified)