CHAPTER ONE IS A DISCUSSION OF ANALYTICAL TECHNIQUES AS THEY ARE APPLIED IN THE FORENSIC LABORATORY. INCLUDED IS A THEORETICAL DISCUSSION OF THE PRINCIPLES OF LIQUID CHROMATOGRAPHY AND CHEMICAL IONIZATION MASS SPECTROSCOPY AS THEY APPLY TO THIS THESIS. CHAPTER TWO IS DEVOTED TO THE INSTRUMENTATION AND METHODOLOGY USED TO PERFORM LIQUID CHROMATOGRAPHIC ANALYSIS. THE SUCCESSFUL APPLICATION OF HIGH PERFORMANCE COLUMNS CAN BE REALIZED ONLY WHEN THE PROPER EQUIPMENT AND TECHNIQUES ARE EMPLOYED. FINALLY, IN CHAPTER THREE, METHODS ARE DEVELOPED FOR THE ANALYSIS OF BALL-POINT PEN INKS AND EXPLOSIVE RESIDUES. THE INK ANALYSIS INVOLVES A SIMPLE EXTRACTION PROCEDURE FOLLOWED BY HIGH PERFORMANCE ADSORPTION CHROMATOGRAPHY. EXPLOSIVE RESIDUE ANALYSES CONSIST OF ISOLATING THE EXPLOSIVE OF INTEREST BY HIGH PERFORMANCE ADSORPTION CHROMATOGRAPHY AND IDENTIFYING THE COMPONENTS OFF-LINE BY CHEMICAL IONIZATION MASS SPECTROSCOPY. RESULTS INDICATE THAT BOTH THESE METHODS SHOULD BE USEFUL IN THE FORENSIC LABORATORY. (AUTHOR ABSTRACT)